Kidney injury molecule-1: potential biomarker of acute kidney injury and disease severity in patients with COVID-19
نویسندگان
چکیده
منابع مشابه
Acute Kidney Injury in Adult Iraqi Patients with COVID-19 Infection
Results: The incidence of AKI was 23.2%. AKI had significant correlation with older age (p-value 0.006) and hypertension (p-value 0.034) . Chest pain and abdominal pain were more common in patients with than those without AKI. Also Mean serum concentration of inflammatory markers ( D-dimer and C-reactive protein (CRP)) in patients with AKI was 1863.6±1599 ng/ml and 66.65±60.81 ng/ml, compared ...
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Acute Kidney Injury (AKI) occurs if the kidneys suddenly lose their ability to remove waste products. When the kidneys lose their ability to filter, dangerous levels of waste products can accumulate, which can upset the chemical composition of the blood and urine. Chemotherapy is one of the methods used to treat or temporarily reduce cancer by using certain medications. The main task of this tr...
متن کاملKidney injury molecule-1 (KIM-1): a novel kidney-specific injury molecule playing potential double-edged functions in kidney injury.
Kidney injury molecule-1 (KIM-1), a recently discovered transmembrane protein, is expressed in dedifferentiated proximal renal tubular epithelial cells in damaged regions. It may participate in the progress of renal injury or repair. Many studies have illustrated the different functions of KIM-1 in various renal diseases including protective functions in acute kidney injury and damaging functio...
متن کاملNetrin-1: a potential universal biomarker for acute kidney injury.
ACUTE KIDNEY INJURY (AKI) is commonly associated with high mortality and morbidity rates, which strongly depend on the time of the diagnosis to allow therapeutic interventions. Recent studies clearly indicate that routine assessments of kidney function based on serum creatinine and blood urea nitrogen measurements and a fall in urine output are outdated because they fail to identify early stage...
متن کاملUrinary kidney injury molecule-1 in patients with IgA nephropathy is closely associated with disease severity.
BACKGROUND The pathological characteristics of IgA nephropathy (IgAN) are highly variable. Urinary kidney injury molecule-1 (KIM-1) is a sensitive biomarker for proximal tubule injury. The aim of the study is to investigate the value of KIM-1 as a biomarker for assessing the renal injury in IgAN. METHODS The levels of urinary KIM-1 in 202 patients with IgAN, 46 patients with other renal disea...
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ژورنال
عنوان ژورنال: Journal of Nephrology
سال: 2021
ISSN: 1121-8428,1724-6059
DOI: 10.1007/s40620-021-01079-x